Not to be confused with Bubo, the nickname of Buboicullaar, a Frog-Dog assassin.

Buboe is justifiably known as the plague planet, being second only to after Rex Nebular's refrigerator as one of the unhealthiest locations in the universe. There are hotels on Buboe, but the atmosphere is so unhealthy, visitors may as well move straight into the hospital to save time. The inhabitants once had extremely strong immune systems but inbreeding and unnecessary vaccinations have taken their toll. Don’t eat here. We mean it. Buboe’s main exports are deadly diseases.